The last thing D.J. said to me before he went frolicking across the Canadian wilderness was, "I will kill you if you do not use the Oxford comma."
But as someone who has the AP Stylebook right next to the Bible in his nightstand, my response? "I'd like to see him try."
In case you are unaware or fell asleep in Mrs. Smith's third grade English class, the Oxford — or serial — comma is used after the penultimate item in a list of three or more items. But unless used in instances where it could reduce ambiguity, it's rather pointless.