Facing a lefty for a second straight night, Bob Melvin had removed Billy Burns, Stephen Vogt and Mark Canha from the lineup.
Coco Crisp will get the start in center in place of Burns, while Josh Phegley will catch Chris Bassitt. Yonder Alonso will make his first start with the A's.
[REWIND: Hill's wild ride gets A's started on wrong foot]
Chicago White Sox:
1. Adam Eaton (L) RF
2. Jimmy Rollins (S) SS
3. Jose Abreu (R) 1B
4. Todd Frazier (R) 3B
5.