Wednesday Night
| Favorite | Underdog | Venue | Time (ET) | Network | Line |
| Bowling Green Falcons | Western Michigan Broncos | Waldo Stadium (WMU) | 8:00 | ESPN2 | -3 |
| Northern Illinois Huskies | Buffalo Bulls | University of Buffalo Stadium | 8:00 | ESPNU | -6 |
November means more weeknight MACtion, and this Wednesday is no different.