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Notre Dame vs. Ohio State Football: Point Spread & Betting Odds for Week 1

After a second-half meltdown in last year’s bowl game against Oklahoma State, Notre Dame (0-0) should be eager to get back on track in 2022. The Irish will be led by Marcus Freeman, starting his first season as Notre Dame’s head coach. Coincidentally, Freeman’s college days were served playing linebacker for the Buckeyes. He was also an assistant coach at Ohio State in 2010, so he will be very familiar with the surroundings. That experience should provide the Irish players some insight into what to expect inside the Horseshoe.

Ohio State (0-0) expects to pick up where it left off in 2021.