Robbie Brady, who injured his quad during the first half of Saturday's win over Cardiff, is a "major doubt", according to Norwich manager Alex Neil.
But Martin Olsson is available again following a hamstring injury.
Wigan midfielder Nick Powell is a doubt after being withdrawn against Sheffield Wednesday with a groin problem.
Defender Nathan Byrne could make his debut but Reece James (ankle), Andy Kellett (knee), Kyle Knoyle (elbow) and Donervon Daniels (knee) are out.
Match facts
- Norwich have conceded just six goals in eight league meetings with Wigan (W3 D3 L2) and never more than once in a game.