SANTA CLARA, Calif. -- San Francisco 49ers quarterback Trey Lance left Sunday's game against the Seattle Seahawks with 2:20 left in the first quarter with a right ankle injury and will not return.
Lance stayed on the field for a few moments in obvious pain after taking a hit from Seahawks linebacker Cody Barton. His right leg was put in an air cast and his teammates quickly gathered around him to offer words of encouragement before he left the field on a cart and headed to the locker room.
With 2:33 to go in the opening quarter, the Niners ran a zone-read play in which Lance had the option to hand it off to receiver Ray-Ray McCloud or keep it.