The Buffalo Bills upset the Minnesota Vikings in a big way, Baker Mayfield made his debut, and the New Orleans Saints outlasted the Atlanta Falcons in a NFC South OT battle. And it might be time to panic for the Dallas Cowboys and Oakland Raiders, among others.
All that and more in Week 3's biggest takeaways from NFL Nation.
The Saints are 2-1 by the skin of their teeth, but they still have major problems on defense after allowing Matt Ryan to throw for 374 yards and five touchdowns.