Week 1 of the NFL season never goes exactly according to plans.
The New England Patriots and Baltimore Ravens were favorites in their matchups, but both surprised with huge blowout wins that were well above the betting lines for those games. The Buffalo Bills, Tennessee Titans and San Francisco 49ers were all road underdogs, yet all three earned victories.
More betting upsets could be in store in Week 2. Here's a look at the full schedule of games, along with the lines and predictions for each of the 16 matchups.
Week 2 NFL Odds and Picks
Picks are in bold and made against the spread.