As was the case a year ago, Week 2 of the 2020 NFL season brought with it several notable fantasy-relevant injuries. While last year's brutal Week 2 featured injuries to quarterbacks Ben Roethlisberger and Drew Brees, this year's edition had several key injuries at the running back position.
Saquon Barkley is out for the year with a torn ACL. Christian McCaffrey is going to miss time with knee and ankle issues, and Raheem Mostert is expected to miss at least Week 3 with an MCL sprain. Additionally, the San Francisco 49ers could be without backup Tevin Coleman.