The are likely to rely heavily on and Richie James at wideout when they face off against the Green Bay Packers on Thursday Night Football.
Early Wednesday evening, the club announced starting receivers Deebo Samuel and Brandon Aiyuk have been officially downgraded to out and placed on the team's reserve/COVID-19 list along with tackle Trent Williams.
Samuel was already considered out Thursday with a hamstring injury.
According to FantasyPros, both James and Taylor are available in more than 99 percent of Yahoo and ESPN fantasy leagues. Managers should be wary of adding either player unless they've exhausted all other options as the Niners prepare to start backup Nick Mullens at quarterback.