San Francisco absolutely stunk earlier this season, starting 1-4 straight up and 1-3 against the spread, but as the lines have risen in the 49ers' favor they're now 2-1 ATS over their last three games. San Francisco will play as a large divisional road dog when it visits the St. Louis Rams on Sunday afternoon.
Point spread: The Rams opened as 7.5-point favorites; the total was 39 early in the week, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
NFL pick, via Odds Shark computer: 30.