The two starting quarterbacks will take center stage Sunday when the Minnesota Vikings host the San Francisco 49ers as solid home favorites at the sportsbooks for an intriguing Week 1 NFC matchup.
San Francisco's Jimmy Garoppolo will put his perfect 7-0 record as a starter on the line against Minnesota's Kirk Cousins, who signed a fully guaranteed three-year contract worth $84 million as a free agent in the offseason.
NFL point spread: The Vikings opened as five-point favorites; the total was 46.5 early in the week, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
NFL betting pick, via OddsShark computer: 25.