Drew Brees
CreditGail Burton/Associated PressThe Ravens are the only team Drew Brees has never beaten, and in this classic offense vs. defense matchup, he has his work cut out for him.
Brees, who became the N.F.L.’s career passing leader in his last start, is well-rested after a bye-week and has shown no signs of slowing down, with his average of 331.6 passing yards a game representing his highest effort since 2011. He stands an extremely good chance of getting the one touchdown pass he needs to become the fourth player in N.F.L. history to have thrown 500 — Brees has failed to throw a touchdown pass just 33 times in 254 career games — but keeping up his yardage average could be tough against a defense allowing just 214.