Week 7 was the first real chaos week of the 2018 season: four top-ten teams lost to unranked or lesser-ranked teams, and nearly every AP top-25 school struggled:
- Four top-ten teams -- Georgia, West Virginia, Washington, and Penn State -- lost.
- Four other top-25 teams -- Wisconsin, Miami, Colorado, and Auburn -- also lost.
- Notre Dame, Texas, Central Florida, Texas A&M, and South Florida all won by one score against unranked teams.
- Ohio State and Florida both won by double digits, but looked sloppy and vulnerable doing so.
- Alabama's Tua Tagovailoa completed just 54.