In Week 13, five NFL franchises currently in playoff positions are underdogs.
Of the quintet, Buffalo and Pittsburgh appear to have the best chance of covering and possibly winning outright.
The Bills head to AT&T Stadium on Thanksgiving to face a Dallas team that has struggled against squads with winning records.
Pittsburgh faces Cleveland for the second time in three weeks, and despite another quarterback change, it is in a good position to enact revenge and gain a stronghold in the race for the AFC's No. 6 seed.
NFL Week 13 Schedule
All Times ET
Odds via Caesars; predictions against the spread in bold
Thursday, November 28
Chicago (-3) at Detroit (12:30 p.