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The San Francisco 49ers will be without the 2023 Offensive Player of the Year for several weeks, as All-Pro running back Christian McCaffrey was placed on injured reserve due to calf tightness as well as Achilles tendinitis.
McCaffrey will be sidelined for at least four games following the move, meaning that his earliest chance to return will be against the Seattle Seahawks on Oct. 10.
The 28-year-old's upcoming absences are also a tough blow for fantasy managers, as he finished as the No. 1 running back in both standard and PPR leagues in 2023.