At a certain point, injuries just don't cut it as an excuse. Ditto for quarterback play.
We've reached that point with the San Francisco 49ers, who on Sunday dropped to 3-5 with a multi-score loss to the division-rival Arizona Cardinals despite the fact quarterback Jimmy Garoppolo completed 28 of 40 passes for 326 yards and two touchdowns, despite the fact a finally-healthy pass-catching corps was quite productive, and despite the fact the Cardinals were altogether more depleted than they were.
Garoppolo threw an interception and took five sacks. He hasn't made more than a handful of high-impact throws all season and is certainly not a tremendous asset.