The Buffalo Bills backfield remains haggard as we approach the weekend.
Both LeSean McCoy (hamstring) and Karlos Williams (concussion) missed practice again on Friday, per Chris Brown of the team's official website.
Williams remains in concussion protocol and appears a long shot to play Sunday versus the Tennessee Titans.
While Rex Ryan wouldn't rule out Shady on Thursday, that McCoy missed practice again doesn't bode well for the back.
With the injuries mounting, Boobie Dixon will likely get the start, with newly signed Dan "Boom" Herron a candidate to see a heavy workload out of the Bills' backfield.