The Houston Texans are 5-0 straight up and 3-1-1 against the spread over their last five road games. Meanwhile the Philadelphia Eagles are only 3-3 SU and 1-5 ATS over their last six home games. So the NFL betting trends seem to favor Houston heading into Sunday afternoon's big game at Philadelphia.
NFL point spread: The Texans opened as 3.5-point favorites; the total was 45 early in the week, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
NFL betting pick, via OddsShark computer: 25.0-21.8 Eagles (NFL picks on every game)
Why the Texans can cover the spread
Houston just bounced back from that loss to Indianapolis two weeks ago to beat the Jets in New Jersey last Saturday 29-22.