NFL Nation's reporters assess the biggest injuries across the league for Week 2.
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AFC EAST
Defensive end Shaq Lawson (hamstring) did not practice Wednesday after being injured in the fourth quarter of Sunday's opener. He started that game in place of Trent Murphy, who the Bills put on a managed rep count as he recovers from a preseason groin injury. If Lawson cannot play this Sunday, Murphy would likely be thrust into more of a full-time role, although Buffalo signed former Browns defensive end Nate Orchard this week as insurance.