Striker Toni Martinez could make his debut for Oxford in their FA Cup fourth-round clash with Newcastle.
Martinez joined the club on loan from West Ham on Monday and is eligible to play in the competition.
But boss Michael Appleton may well decide to stick with the team that beat Rochdale 4-0 in League One last weekend.
Defenders Christian Ribeiro and Sam Long are back in training after lengthy injury absences and are set for a run-out in Monday's friendly against Vancouver Whitecaps.
Newcastle boss Rafael Benitez will use the depth of his squad once again as he attempts to manage the dual demands of the FA Cup and the quest for promotion back to the Premier League.
PUT BEDTIME ON BLAST
