Newcastle's club record signing Alexander Isak could make his first league appearance for four months after playing in two cup ties since his return from a thigh injury.
Fulham striker Aleksandar Mitrovic returns from a one-match suspension to face his former club.
Left-back Antonee Robinson is banned for accumulating five yellow cards.
CHRIS SUTTON'S PREDICTION
It was too little, too late for Newcastle when they brought their big guns off the bench to chase the game against Sheffield Wednesday in the FA Cup, but I don't think that defeat has any bearing on their league form.