Newcastle remain without Sean Longstaff, though he is making good progress in his recovery from a foot problem, according to boss Eddie Howe.
Jacob Murphy is doubtful with a groin issue, while Matt Ritchie, Emil Krafth and Jamaal Lascelles are unavailable.
Brighton trio Adam Webster, Joel Veltman and Solly March are still ruled out because of injury.
Adam Lallana, Tariq Lamptey, Jeremy Sarmiento and Jakub Moder are long-term absentees.
Head coach Roberto de Zerbi says goalkeeper Robert Sanchez, who was not in the matchday squad against Arsenal, will also not be involved on Thursday, explaining "he wants it this way, not me and not the club".