Manchester United will face Newcastle in the Carabao Cup fourth round in a repeat of last season's final.
West Ham host Arsenal, Bournemouth are at home to Liverpool and Everton host Sean Dyche's old club Burnley in three more all-Premier League ties.
Fulham visit Championship side Ipswich and Chelsea host Blackburn.
There will be at least two EFL sides in the quarter-finals, with League Two Mansfield at home to Port Vale and Exeter playing Middlesbrough.
The fourth-round ties will take place in the week commencing 30 October.
Fourth-round draw in full
Mansfield v Port Vale
Ipswich v Fulham
Manchester United v Newcastle
Bournemouth v Liverpool
Chelsea v Blackburn
West Ham v Arsenal
Everton v Burnley
Exeter v Middlesbrough
