Paul Goldschmidt, Cody Bellinger and Aaron Judge homered for the Yankees on the first three pitches from Milwaukee's Nestor Cortes, part of seven New York home runs in the first three innings on Saturday.
Major League Baseball said it was the first time a team hit home runs on its first three pitches since tracking of pitch counts began in 1988.
Austin Wells also hit a solo homer in the first as New York burst ahead 4-0. The Yankees hit four home runs in the first inning for the first time in the team's over 100-year history.