New York Red Bulls
- OUT: Florian Valot (M) - torn ACL
- QUESTIONABLE: Bradley Wright-Phillips (F) - groin injury
- QUESTIONABLE: Aaron Long (D) - hamstring injury
- QUESTIONABLE: Vincent Bezecourt (M) - knee injury
- QUESTIONABLE: Andreas Ivan (M) - ankle injury
Vancouver Whitecaps FC
- OUT: Michael Baldisimo (M) - left ankle contusion
- OUT: Jasser Khmiri (D) - left knee injury
- OUT: David Norman Jr. (F) - right foot surgery
- OUT: Yordy Reyna (F) - left hamstring strain
- OUT: Lass Bangoura (F) - left hamstring strain
- OUT: Doneil Henry (D) - left hamstring injury
- QUESTIONABLE: Felipe (M) - right foot sprain/contusion
- QUESTIONABLE: Jon Erice (M) - left ankle sprain