The last Copa America Centenario quarterfinal pits the reigning champions of each participating confederation against each other. In the red corner: Chile, winner of the 2015 Copa America, slightly bruised by the experience of losing in the group stage to the team it beat to win the CONMEBOL crown last year (Argentina). In the green corner: Mexico, winner of the 2015 Gold Cup, and winner of Group C at this tournament.
El Tri is unbeaten under head coach Juan Carlos Osorio (though no longer perfect: the 1-1 draw against Venezuela was the first game Mexico hasn't won since JCO officially took charge of the team).