Jose Reyes has some pitching fun — and a 54.00 ERA

Jose ReyesWASHINGTON — Jose Reyes pitched about as effectively as he has hit and fielded this year.

A historic 25-4 loss to the Nationals for the Mets on Tuesday night — the worst loss by run differential in their 57-year history — wrapped up on an appropriately ghoulish note at Nationals Park when Reyes, the longtime Met, took the mound for the bottom of the eighth inning and got knocked around for six runs, including two homers. The 35-year-old threw an astounding 48 pitches to get through his professional pitching debut, leaving with his career ERA of 54.00.

“When you’re on the mound, before you throw a pitch, it’s fun,” Reyes said. “But when you start to see people hit a homer and stuff,…