The Mets were unable to complete the four-game sweep in Washington DC, losing to the Nationals 4-2 in the opening series finale.
Carlos Carrasco’s first start of the 2022 season began the way many of his starts did in 2021; with two outs, he hung a pitch to Nelson Cruz, which Cruz sent into the seats for his first home run as a National, giving the Nationals an early 1-0 lead. Josh Bell laced a hard-hit single after that and it looked like the inning might unravel on Cookie, but he was able to limit the damage by getting Kiebert Ruiz to fly out to right field to end the inning.