All odds via FanDuel Sportsbook
- Baltimore Ravens @ Tennessee Titans: +5.5
- San Francisco 49ers @ Cleveland Browns: +9.5
- Washington Commanders @ Atlanta Falcons: -1.5
- Carolina Panthers @ Miami Dolphins: -14.5
- Minnesota Vikings @ Chicago Bears: +3
- Indianapolis Colts @ Jacksonville Jaguars: -3.5
- New Orleans Saints @ Houston Texans: +1.5
- Seattle Seahawks @ Cincinnati Bengals: -3
- New England Patriots @ Las Vegas Raiders: -2.5
- Detroit Lions @ Tampa Bay Buccaneers: +3
- Arizona Cardinals @ Los Angeles Rams: -7
- Philadelphia Eagles @ New York Jets: +6.