All odds via ESPN BET
- Baltimore Ravens @ Kansas City Chiefs: -3
- Green Bay Packers @ Philadelphia Eagles: -2.5
- Carolina Panthers @ New Orleans Saints: -4
- Houston Texans @ Indianapolis Colts: +3
- Jacksonville Jaguars @ Miami Dolphins: -3.5
- Arizona Cardinals @ Buffalo Bills: -6.5
- Pittsburgh Steelers @ Atlanta Falcons: -3.5
- Minnesota Vikings @ New York Giants: +1.5
- Tennessee Titans @ Chicago Bears: -3.5
- New England Patriots @ Cincinnati Bengals: -8.5
- Denver Broncos @ Seattle Seahawks: -6
- Las Vegas Raiders @ Los Angeles Chargers: -3
- Washington Commanders @ Tampa Bay Buccaneers: -3.