TEMPE, Ariz. -- Arizona Cardinals coach Bruce Arians did not have an update on the health of either of his two starting guards, but he was impressed with one of their replacements.
Both right guard Evan Mathis and left guard Mike Iupati left Thursday's 33-21 win over the San Francisco 49ers with ankle injuries and did not return. Mathis limped off the field at the end of the first half, and Iupati went down in the third quarter.
The Cardinals were still evaluating both injuries as of Friday afternoon, Arians said.