If you want to throw on the San Francisco 49ers defense, it all starts with silencing the man who leads the NFL with 115 quarterback hits since 2021: Nick Bosa.
No other player in the NFL has even 100 quarterback hits over this span. Maxx Crosby is a distant second with 97. After Crosby, the next-best player has 89 (a tie between Myles Garrett and Micah Parsons).
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To be clear, a “quarterback hit” is tallied whenever a defender puts the quarterback on the ground.