Reilly Smith, Aleksander Barkov and Aaron Ekblad scored in the second period to lead the Panthers to a 5-1 victory over the Islanders on Tuesday night.
Vincent Trochek and Jonathan Huberdeau added goals in the third period, and Roberto Luongo finished with 33 saves for the Panthers.
Brock Nelson had his 10th goal of the season for the Islanders, who snapped a five-game home winning streak and a 10-game stretch overall without a loss in regulation (8-0-2). Jaroslav Halak had 12 saves.
Halak had been 4-0-2 in his last six games. He lost for the first time since Nov.