The winless Cleveland Browns and San Francisco 49ers are the front-runners at midseason for the No. 1 overall pick in the 2018 NFL draft, and the Indianapolis Colts and New York Giants aren't far behind.
The Browns have a strong need for a quarterback, and the 49ers have flexibility after trading a second-round pick to the Patriots for Jimmy Garoppolo. The Colts, meanwhile, already have their quarterback in Andrew Luck but could be positioned to take a top defensive player or an explosive player on offense, such as Penn State running back Saquon Barkley.