Blake Martinez during Giants practice on Sept. 17. Credit: Matthew Swensen/Matthew Swensen
49ERS (1-1) AT GIANTS (0-2), 1 p.m., Metlife Stadium
VITALS
Line: 49ers by 3 1/2; O/U 42 1/2
TV: Ch. 5 (Kevin Burkhardt, Daryl Johnston)
Radio: WFAN-660 (Bob Papa, Carl Banks, Howard Cross), Sirius 121; XM 227.
INJURY IMPACT
GIANTS
DOUBTFUL: DB Adrian Colbert (quad); QUESTIONABLE: CB Brandon Williams (groin).
49ERS
OUT: QB Jimmy Garoppolo (ankle), RB Tevin Coleman (knee), DE Dee Ford (back), LB Dre Greenlaw (quad), TE George Kittle (knee), RB Raheem Mostert (knee); QUESTIONABLE: CB Ahkello Witherspoon (hamstring).