History has taught us to never count the Giants out against the New England Patriots. But with a loss to the Vikings on Sunday that dropped the Giants to 2-3 overall and an undefeated Patriots team, the odds are against Big Blue Thursday night.
The Giants, per DraftKings Nation, are 16-point underdogs.
That is the biggest predicted spread amongst all of the week six matchups listed on the DraftKings Nation page. The next closest spread is the Cleveland Browns being 10.5-point favorites over the Cincinnati Bengals.
The 31 points per game scored by the Patriots this season rank third in the NFL and their 279.