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Giants-Cowboys Week 10 odds: The biggest point spread of the 2023 season

lost 40-0 to the Dallas Cowboys (-15.5) in one of the most lopsided losses in franchise history. That was with an almost fully healthy roster.

How, then, is anyone supposed to set betting odds for the rematch if the Giants don’t even have their starting quarterback? DraftKings Sportsbook has made an attempt by setting an opening point spread that will be the largest for any NFL game this season, if the line holds.

The Cowboys are currently 15.5-point favorites with -1050 odds on the moneyline. The over/under for the game is set at 39.