An undermanned New York Giants offense that will be without Saquon Barkley faces the San Francisco 49ers (-10, 44.5) at Levi's Stadium on Thursday night.
The 49ers moved to 2-0 with a road win over the Rams in Week 2, while the Giants rallied from 21 points down to knock off the Cardinals.
So what can we expect from a betting standpoint for Thursday night's game?
Betting analysts Tyler Fulghum, Erin Dolan, Eric Moody and Seth Walder are here to provide their thoughts.