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10 storylines to follow when Giants face 49ers

1. SO THEY MEET AGAIN

The New York Giants (2-2) and San Francisco 49ers (1-3) meet for the fifth time in five seasons this Sunday night at MetLife Stadium. Among non-division opponents, only Green Bay and Atlanta have faced the Giants more often in that span with four meetings apiece. The Week 5 matchup will break a 19-19 tie, including 4-4 in the postseason, in the all-time series that dates back to 1952. The 38 games have been decided by a total of eight points in the Giants’ favor, or 0.21 points per contest. However, the 49ers won their most recent meeting, 16-10, last season on the Giants’ home turf.