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San Francisco could be the New Orleans Saints kryptonite

The New Orleans Saints have three losses this season.

One was to the Los Angeles Rams, a game in which Drew Brees injured his thumb, sidelining him for over the next month. The second was to the Atlanta Falcons, a divisional foe that usually plays New Orleans pretty well. The Saints defeated the Falcons a few weeks later.

The third was against the fifth-seeded San Francisco 49ers.

The Niners still have a chance to secure a top-two seed in the NFC playoffs, but they’ll need to win their second matchup with the Seattle Seahawks.