The Week 13 NFL schedule for the 2022 season is stacked with great matchups, and we've got you covered heading into the weekend. Our NFL Nation reporters offer the biggest keys and bold predictions for each matchup.
Additionally, ESPN Stats & Information provides a big stat to know and a betting nugget for each contest, and our Football Power Index (FPI) goes inside the numbers with game projections. ESPN researcher Kyle Soppe hands out helpful fantasy football intel, as well. Finally, Seth Walder and Eric Moody give us final score picks for every game.