Week 11 featured arguably the best player performance of the 2021 NFL season. Colts running back Jonathan Taylor ran for 185 yards and four touchdowns, and he added a 19 more yards and a fifth score on three catches. Indianapolis pulled off the big upset of the Bills behind Taylor's huge day, scoring 41 points. The Vikings also upset the Packers on a final-play field goal, and receiver Justin Jefferson helped them get there with 169 receiving yards and a pair of TDs.
But perhaps the biggest upset of the week came with the Texans' 22-13 victory over the Titans.