That didn't look very pleasant.
At 13:42 in the 2nd quarter, Buccaneers defensive end Jacquies Smith beat tackle Zach Strief off the edge and swatted Drew Brees' arm, forcing one of two fumbles against the QB on the night.
Here's a replay of the hit.
It's one thing to see the Saints defense struggle, but a hampered Brees is good for no one and definitely doesn't help an otherwise lackluster offense. Per ESPN, Brees played down the significance of the hit stating "he'll be ok" and it doesn't yet appear like there was any considerable damage on his shoulder.