The NFL’s Sunday action ends in what could be a snowy Orchard Park, as the struggling San Francisco 49ers head to Buffalo to take on Josh Allen and the Bills.
Check down below to see Pats Pulpit’s picks tonight and head to the comment section to further discussion Friday night’s action.
Patriots rooting guide
Go 49ers! End the night by rooting against the AFC East. | 8:20 p.m. ET, NBC
Patriots picks
Oliver Thomas: The 49ers, standing at 5-6, are coming off a 28-point loss, their worst under Kyle Shanahan since 2018.