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Super Bowl 50 Betting Odds: Cards, Patriots Hit Divisional Round as Favorites

Despite not having home-field advantage in potential conference championship matchups against the top seeds, the second-seeded Arizona Cardinals (13-3) and New England Patriots (12-4) are the favorites to win Super Bowl 50 on February 7.

The Cardinals are 17-4 to win the big game at sportsbooks monitored by Odds Shark, while the defending Super Bowl champion Patriots are 9-2. And both teams are also favored to win the NFC and AFC, respectively.

Arizona will host the Green Bay Packers (11-6) for the second time in four weeks on Saturday after routing them 38-8 as six-point home favorites in the first meeting.