The San Francisco 49ers (3-3) travel across the country to take on the New England Patriots (2-3) Sunday in a Week 7 showdown between two teams who have underperformed thus far. Kickoff from Gillette Stadium is at 4:25 p.m. ET. Below, we analyze the 49ers-Patriots Week 7 matchup, including the betting odds, spread and lines, and look at the best NFL betting options.
49ers at Patriots betting odds and lines
Odds via BetMGM; access USA TODAY Sports' betting odds for a full list. Lines last updated Thursday at 11:33 p.