Patriots open as massive underdogs vs. banged-up 49ers in Week 4 originally appeared on NBC Sports Boston
The San Francisco 49ers haven't played great football through their first three games despite coming into the 2024 NFL season among the Super Bowl favorites, but oddsmakers seem pretty confident in their ability to beat the New England Patriots in Week 4.
The Patriots have opened as 10.5-point underdogs, per odds at Fanatics Sportsbook.
That's a pretty massive number, but not all that surprising when you consider just how poorly the Patriots played in Week 3.