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Patriots list 20 players on injury report ahead of Bills game

The bad news? The 1-5 Patriots opened as 9.5-point underdogs going into Sunday’s home showdown against the Buffalo Bills.

The even worse news? An already shorthanded Patriots roster bit by the injury bug submitted a lengthy injury report on Wednesday evening.

In total, New England’s first injury report of the week listed 20 total players — including six who did not participate in practice at Gillette Stadium on Wednesday morning.

Here’s the full list:

DID NOT PARTICIPATE

OT Trent Brown, Chest

TE Hunter Henry, Ankle

CB Jonathan Jones, Knee

OL Riley Reiff, Knee

LB Josh Uche, Knee/Foot

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DL Keion White, Concussion

LIMITED PARTICIPATION

C David Andrews, Ankle

DL Christian Barmore, Knee

DB Cody Davis, Knee

WR Demario Douglas, Concussion

S Kyle Dugger, Foot

DL Trey Flowers, Foot

DL Davon Godchaux, Ankle

DB Jack Jones, Hamstring

OL Mike Onwenu, Ankle

DB Jabrill Peppers, Knee

WR JuJu Smith-Schuster, Concussion

RB Rhamondre Stevenson, Ankle

G Cole Strange, Knee

CB Shaun Wade, Shoulder

The Patriots have already lost several key contributors to injury this season, especially on the defensive side of the ball in linebacker Matthew Judon (biceps) and cornerback Christian Gonzalez (shoulder).