The Patriots' seven inactive players are Dominique Easley (hip), Ryan Wendell (illness), Trey Flowers (knee), Nate Ebner, Justin Coleman, Keshawn Martin and James White. Ebner, Coleman, Martin and White are healthy scratches because they weren't on the injury report, but Ebner went through a pregame workout that indicated he was a game-time decision due to an unknown injury. Ebner hasn't been on the injury report all season.
Rufus Johnson and Travaris Cadet will make their Patriots debuts today. Tavon Wilson also returns to the lineup after missing the opener with a quad injury.
LeSean McCoy is active for the Bills after injuring his hamstring this week.